Practical Dermatology® was at the American Academy of Dermatology 2024 Annual Meeting in San Diego (AAD 2024) reporting on the latest research findings on innovative therapies and insights into managing complex dermatological disorders. From pioneering trials showcasing the efficacy of novel topical treatments, to advancements in systemic therapies such as targeted oral peptides for psoriasis and oral JAK-1 inhibitors for prurigo nodularis, these studies showcased promising avenues for improving patient care.